Annabel_Chen

Lab Members

S.H. Annabel Chen Ph.D.

Director of The Clinical Brain Lab

Assistant Professor

Clinical Neuropsychologist

Clinical Psychology Program

Curriculum Vitae

Contact

Tel: +886-2-3366-3105

Fax: +886-2-2363-1463

Email:shachen[at]ntu.edu.tw

National Taiwan University

Department & Graduate Institute of Psychology

1, Sec. 4, Roosevelt Road,

Taipei 106, Taiwan

Research Background and Interests

My research experiences are varied and have involved both adult and child populations. I have been involved in animal drug studies, human clinical, and experimental neuropsychological research, including cognitive rehabilitation. The focus of my research has been in using functional imaging (PET and fMRI) to better understand neural systems involved in cognitive processes in normal and clinical adult populations. My dissertation examined patients with post-concussion sequelae from mild head injury using functional neuroimaging (PET). I have been involved in fMRI research examining language processing, executive functions, and affective memory in normal adults, as well as, assessing neural systems used in motor timing/timing perception in patients with Parkinson's Disease.

I am interested in using fMRI and single-pulse TMS (Transcranial Magnetic Stimulation) to investigate neural substrates involved in executive functions, such as working memory and mental flexibility. The goal is to apply these paradigms to study the cerebro-cerebellar circuitry in clinical groups, such as mild head injury, dyslexia, autism, and alcoholism. I am also interested in ethical and technical issues involved with tasks development and standardization of clinical fMRI.

Professional Experience

Education
2004	Post Doctoral Research Affiliate Lucas Magnetic Resonance Spectroscopy/Imaging Center Stanford University School of Medicine, Stanford, California
2001	Post Doctoral Fellowship (Residency) Adult Clinical Neuropsychology (APPCN Accredited) Medical College of Wisconsin, Milwaukee, Wisconsin
1999	Clinical Psychology Internship Clinical Neuropsychology Specialty Track (in accord with INS-Division 40 Guidelines) West Virginia University School of Medicine (APA Accredited) Morgantown, West Virginia
1999	Doctor of Philosophy Clinical Rehabilitation Psychology with emphasis in Clinical Neuropsychology Purdue University at Indianapolis, Indiana (APA Accredited)
1995	Masters of Science Clinical Rehabilitation Psychology Purdue University at Indianapolis, Indiana
1992	Bachelor of Social Sciences Honours in Psychology National University of Singapore
1991	Bachelors of Arts Majors: Economics and Psychology; Minor: Statistics National University of Singapore

Recent Publications

Schulte T, Chen SHA, Muller-Oehring EM, Adalsteinsoon E, & Pfefferbaum A (2006) fMRI Evidence for individual differences in premotor modulation of extrastriatal visual-perceptual processing of redundant targets. NeuroImage, 30(3), 973-982. (SCI)

Desmond JE, Chen SHA, & Shieh PB (2005) Right cerebellar transcranial magnetic stimulation (TMS) impairs verbal working memory performance. Annals of Neurology, 58, 553-560. (SCI)

Chen SHA., & Desmond JE (2005). Temporal Dynamics of Cerebro-Cerebellar Network Recruitment During a Cognitive Task. Neuropsychologia, 43(9), 1227-1237 (SCI)

Chen SHA., & Desmond JE (2005). Cerebro-cerebellar networks during articulatory rehearsal and verbal working memory tasks. NeuroImage, 24(2), 332-338. (SCI)

Kirschen MP, Chen SHA, Schraedley-Desmond P, & Desmond JE (2005). Load and practice dependent increases in cerebro-cerebellar activation in verbal working memory: An fMRI study. NeuroImage, 24(2), 462-472. (SCI)

Desmond JE, Chen SHA, DeRosa E, Pryor MR, Pfefferbaum A, & Sullivan EV. (2003). Increased Fronto-Cerebellar Activation in Alcoholics During Verbal Working Memory: an fMRI Study. NeuroImage, 19(4), 1510-20. (SCI)

Woods JE 2nd, McKay PF, Masters J, Seyoum R, Chen A, La Duff L, Lewis MJ, June HL. (2003). Differential responding for brain stimulation reward and sucrose in high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats. Alcoholism-Clinical and Experimental Research, 27, 6, 926-936. (SCI)

Sullivan EV, Harding AJ, Pentney R, Dlugos C, Martin PR, Parks MH, Desmond JE, Chen SHA, Pryor MR, De Rosa E, Pfefferbaum A (2003). Disruption of frontocerebellar circuitry and function in alcoholism. Alcoholism-Clinical and Experimental Research, 27, 2, 301-309. (SCI)

Chen SHA, Kareken DA, Fastenau PS, Trexler LE, & Hutchins GD. (2003). A study of persistent post concussion symptoms in mild head trauma using positron emission tomography. Journal of Neurology, Neurosurgery, and Psychiatry, 74, 326-332. (Editor’s Choice) (SCI)

Desmond JE & Chen SHA. (2002). Ethical issues in the clinical application of fMRI: factors affecting the validity and interpretation of activations. Brain and Cognition, 50, 482-497 (SCI)

Kareken DA, Doty RL, Moberg PJ, Mosnik D, Chen SH, Farlow MR, & Hutchins GD. (2001). Olfactory-evoked Regional Cerebral Blood Flow in Alzheimer Disease. Neuropsychology, 15 (1), 18-29. (SCI)

Courses

Abnormal Psychology

Introduction to Clinical Psychology

Child Psychopathology

Child Assessment

Research Seminars in Clinical Psychology

Internship in Clinical Child Psychology

Internship in Clinical Rehabilitation Psychology